KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24C
All Species:
37.88
Human Site:
T666
Identified Species:
59.52
UniProt:
P53992
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53992
NP_004913.2
1094
118325
T666
D
D
R
K
L
I
N
T
D
K
E
K
T
L
F
Chimpanzee
Pan troglodytes
XP_001145058
1094
118246
T666
D
D
R
K
L
I
N
T
D
K
E
K
T
L
F
Rhesus Macaque
Macaca mulatta
XP_001104565
998
107625
M593
S
S
L
A
Q
P
Q
M
M
V
V
S
D
V
A
Dog
Lupus familis
XP_850963
1096
118584
T668
D
D
R
K
L
I
N
T
D
K
E
K
T
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
S656
R
E
E
P
N
Q
R
S
S
A
K
E
I
H
L
Rat
Rattus norvegicus
NP_001102926
1095
118506
T667
D
D
R
K
L
I
N
T
D
K
E
K
T
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513100
1030
112379
K625
N
V
Y
E
A
L
A
K
D
C
V
A
S
G
C
Chicken
Gallus gallus
XP_421617
1147
124543
T719
D
D
K
K
L
I
N
T
D
K
E
K
T
L
F
Frog
Xenopus laevis
NP_001087832
1126
123503
T698
D
D
K
K
L
V
N
T
D
K
E
K
I
L
F
Zebra Danio
Brachydanio rerio
XP_700597
1315
142554
T889
E
D
K
K
L
V
G
T
D
K
E
K
S
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392952
1276
140829
T847
D
D
R
K
I
L
G
T
E
K
E
K
T
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783728
1150
123558
T722
D
D
R
K
L
L
G
T
D
K
E
K
T
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M081
1080
116273
S662
A
E
G
R
A
N
M
S
A
G
E
K
E
A
H
Baker's Yeast
Sacchar. cerevisiae
P53953
876
98925
L471
D
V
A
T
L
S
H
L
G
R
F
S
G
G
Q
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
Y545
M
F
L
F
S
S
Q
Y
Q
D
V
A
S
L
S
Conservation
Percent
Protein Identity:
100
99.5
86.9
94.8
N.A.
26.9
92
N.A.
51.9
75.4
69
59.5
N.A.
N.A.
44.5
N.A.
52.6
Protein Similarity:
100
99.7
87.9
96.1
N.A.
45.8
94.4
N.A.
66.2
82.3
78.1
69
N.A.
N.A.
59.4
N.A.
64.3
P-Site Identity:
100
100
0
100
N.A.
0
100
N.A.
6.6
93.3
80
66.6
N.A.
N.A.
60
N.A.
73.3
P-Site Similarity:
100
100
6.6
100
N.A.
26.6
100
N.A.
33.3
100
93.3
93.3
N.A.
N.A.
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
22.4
30
Protein Similarity:
N.A.
N.A.
N.A.
49.3
41.1
47
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
14
0
7
0
7
7
0
14
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% C
% Asp:
60
60
0
0
0
0
0
0
60
7
0
0
7
0
0
% D
% Glu:
7
14
7
7
0
0
0
0
7
0
67
7
7
0
0
% E
% Phe:
0
7
0
7
0
0
0
0
0
0
7
0
0
0
47
% F
% Gly:
0
0
7
0
0
0
20
0
7
7
0
0
7
14
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
7
% H
% Ile:
0
0
0
0
7
34
0
0
0
0
0
0
14
0
0
% I
% Lys:
0
0
20
60
0
0
0
7
0
60
7
67
0
0
0
% K
% Leu:
0
0
14
0
60
20
0
7
0
0
0
0
0
54
20
% L
% Met:
7
0
0
0
0
0
7
7
7
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
7
40
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
14
0
7
0
0
0
0
0
7
% Q
% Arg:
7
0
40
7
0
0
7
0
0
7
0
0
0
0
0
% R
% Ser:
7
7
0
0
7
14
0
14
7
0
0
14
20
0
7
% S
% Thr:
0
0
0
7
0
0
0
60
0
0
0
0
47
0
0
% T
% Val:
0
14
0
0
0
14
0
0
0
7
20
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _